Scientific papers

In accordance with its mission to support high level research in Belgium, the University Foundation provides financial support towards the publication in high level international journals of scientific papers which report on research in Belgian research groups. Financial support may be granted to partially cover the costs due by the author for illustrations, for page charges and for article processing fees, and for linguuistic control. 

Because the possible support is restricted to Belgian research groups, the regulations and application procedures are only available in French  and in Dutch.

Articles subsidized by the University Foundation

What follows is a list of articles that were subsidized recently by the University Foundation. The titles are ordered by year of publication and by title.

Romy Van Rickstal, Aline De Vleminck, Sebastiaan Engelborghs, Jan Versijpt and Lieve Van den Block

Van Rickstal R, Vleminck A, Engelborghs S, Versijpt J, Van den Block L. (2022) A qualitative study with people with young-onset dementia and their family caregivers on advance care planning: A holistic, flexible, and relational approach is recommended. Palliat Med. Apr 26:2692163221090385. doi: 10.1177/02692163221090385.

Background: Broad consensus exists on the relevance of advance care planning in dementia. Although people with young-onsetdementia and their family are hypothesized to have distinct needs and preferences in this area, they are hardly ever included in studies.
Aim: We aim to explore the experiences with and views on advance care planning of people with young-onset dementia and their family caregivers.
Bruno Bonnechère, Sékou Samadoulougou, Kadari Cisse, Souleymane Tassembedo, Seni Kouanda, Fati Kirakoya-Samadoulougou

Bonnechère, B., Samadoulougou, S., Cisse, K., et al. (2022)  Alcohol consumption and associated risk factors in Burkina Faso: results of a population-based cross-sectional survey. BMJ Open 12:e058005. doi:10.1136/bmjopen-2021-058005

Objectives Lifestyle modifiable risk factors are a leading preventable cause of non-communicable diseases, with alcohol consumption among the most important. Studies characterising the prevalence of alcohol consumption in low-income countries are lacking. This study describes the prevalence of different levels of alcohol consumption in Burkina Faso and its associated factors.
Design Data from the 2013 Burkina Faso WHO STEPwise Approach to Surveillance survey were analysed.
Natacha Biset, Wies Kestens, Dominique Detemmerman, Murielle Lona, Güngör Karakaya, Ann Ceuppens, Stéphanie Pochet and Carine De Vriese

Biset, N.; Kestens, W.; Detemmerman, D.; Lona, M.; Karakaya, G.; Ceuppens, A.; Pochet, S.; De Vriese, C. (2022) Analysis of the Consumption of Drugs Prescribed for the Treatment of Asthma in Belgian Children. Int. J. Environ. Res. Public Health, 19, 548.

Abstract: (1) Asthma is one of the most common chronic diseases in the world among children. The main purpose of this study was to analyze the consumption of asthma medications in order to investigate asthma in children (2–18 years) and the association with health care consumption; (2) a retrospective study using anonymized administrative data for 2013–2018 from the third largest Belgian health insurer was conducted; (3) in 2018, 12.9% of children received at least one asthma medication and 4.4% received at least two packages with a minimum of 30 days between purchases.

Christine Delporte & Muhammad Soyfoo

Delporte C. & Soyfoo M., Aquaporins: Unexpected actors in autoimmune diseases, Autoimmunity Reviews, 2022.

Aquaporins (AQPs), transmembrane proteins allowing the passage of water and sometimes other small solutes and molecules, are involved in autoimmune diseases including neuromyelitis optica, Sj¨ogren’s syndrome and rheumatoid arthritis. Both autoantibodies against AQPs and altered expression and/or trafficking of AQPs in various tissue cell types as well as inflammatory cells are playing key roles in pathogenesis of autoimmune diseases.

Mouctar Sow, Marie-France Raynault & Myriam De Spiegelaere

Sow, M., Raynault, MF. & De Spiegelaere, M. (2022) Associations between socioeconomic status and pregnancy outcomes: a greater magnitude of inequalities in perinatal health in Montreal than in Brussels. BMC Public Health 22, 829.


Comparing health inequalities between countries helps us to highlight some factors specific to each context that contribute to these inequalities, thus contributing to the identification of courses of action likely to reduce them. This paper compares the associations between socioeconomic status (SES) and 1) low birth weight (LBW) and 2) preterm birth, in Brussels and Montreal (in general population, natives-born mothers, and immigrant mothers).

Amélyne Wauters, Julien Tiete, Joana Reis, Isabelle Lambotte, Simone Marchini, and Véronique Delvenne

Wauters A., Tiete J., Reis J.,Lambotte I., Marchini S., and Delvenne V. (2022) Child, adolescent, and parent mental health in general population during a year of COVID‑19 pandemic in Belgium: a cross‑sectional study. Discover Mental Health, vol. 2, issue 1, article 16 (

Background This study aims to evaluate the mental health status of children, adolescents and their parents during the first year of COVID-19 pandemic in Belgium.
Method Analysis compared results before and during the second national lockdown, which started on November 2nd 2020. A cross-sectional online survey was conducted between May 2020 and April 2021.

Camille Hoornaert , Stéphanie Pochet, Sophie Lorent

Hoornaert C, Pochet S, Lorent S. (2022) Development and Delphi validation of a Best Possible Medication History form in Eur J Hosp Pharm Epub. doi:10.1136/ ejhpharm-2021-003095

To develop and validate a standardized Best Possible Medication History (BPMH) form that could be used by clinical pharmacists.
The draft version was presented to a focus group and was adapted following their comments. A three-rounds e-Delphi method was used to validate content, usability and face validity of the BPMH form. We supplemented the quantitative analysis with a qualitative analysis of comments for each Delphi round.

Souleymane Fofana, Cédric Delporte, Rafaèle Calvo Esposito, Moussa Ouédraogo, Pierre Van Antwerpen, Innocent Pierre Guissou, Rasmané Semdé and Véronique Mathieu
Fofana, S.; Delporte, C.; Calvo Esposito, R.; Ouédraogo, M.; Van Antwerpen, P.; Guissou, I.P.; Semdé, R.; Mathieu, V. (2022) In Vitro Antioxidant and Anticancer Properties of Various E. senegalensis Extracts. Molecules, 27, 2583.

Abstract: Although Erythrina senegalensis is a plant widely used in traditional medicine in sub-Saharan Africa, its biological properties have been poorly investigated to date. We first characterized by conventional reactions the composition of several stem bark extracts and evaluated in acellular and cellular assays their pro- or antioxidant properties supported by their high phenolic and flavonoid content, particularly with the methanolic extract.

Olivier Dartevelle, Sergio Altomonte, Gabrielle Masy, Erwin Mlecnik and Geoffrey van Moeseke
Dartevelle, O.; Altomonte, S.; Masy, G.; Mlecnik, E.; van Moeseke, G. (2022) Indoor Summer Thermal  Comfort in a Changing Climate: The Case of a Nearly Zero Energy House in Wallonia (Belgium). Energies, 15, 2410.
Abstract: While the potential impact of climate change mitigation measures is well documented in building sciences literature, there are only relatively sparse studies focusing on the efficiency of adaptation strategies. This paper aims to contribute to this topic by evaluating the extent to which the design of a typical nearly Zero Energy Buildling (nZEB) house in Wallonia (Belgium), and its current operation, could provide summer thermal comfort in a changing climate. Based on calibrated whole
Sébastien Vandenitte
Vandenitte S (2022) Making Referents Seen and Heard Across Signed and Spoken Languages: Documenting and Interpreting Cross-Modal Differences in the Use of Enactment. Front. Psychol. 13:784339. doi: 10.3389/fpsyg.2022.784339

Differences in language use and structures between signed and spoken languages have often been attributed to so-called language “modality.” Indeed, this is derived from the conception that spoken languages resort to both the oral-aural channel of speech and the visual-kinesic channel of visible bodily action whereas signed languages only resort to the latter. This paper addresses the use of enactment, a depictive communicative strategy whereby language users imitate referents in signed and spoken languages.

Lola Seyll and Alain Content
Seyll, L. and Content, A. (2022) Letter-Like Shape Recognition in Preschool Children: Does Graphomotor Knowledge Contribute? Front. Psychol. 12:726454. doi: 10.3389/fpsyg.2021.726454

Based on evidence that learning new characters through handwriting leads to better recognition than learning through typing, some authors proposed that the graphic motor plans acquired through handwriting contribute to recognition. More recently two alternative explanations have been put forward. First, the advantage of handwriting could be due to the perceptual variability that it provides during learning. Second, a recent study suggests that detailed visual analysis might be the source of the advantage of handwriting over typing.

Stijn Vissers, Sigrid Dierickx, Lenzo Robijn, Joachim Cohen, Luc Deliens, Freddy Mortier and Kenneth Chambaere
Vissers, S.; Dierickx, S.; Robijn, L.; Cohen, J.; Deliens, L.;Mortier, F.; Chambaere, K. Physicians’ Experiences and Perceptions of Environmental Factors Affecting Their Practices of Continuous Deep Sedation until Death: A Secondary Qualitative Analysis of an Interview Study. Int. J. Environ. Res. Public Health 2022, 19, 5472.

As previous research has paid little attention to environmental factors affecting the practice of continuous deep sedation until death (CDS), we aimed to explore these using physicians’ experiences and perceptions.

Sophie Opsomer, Emelien Lauwerier, Jan De Lepeleire and Peter Pype

Opsomer S, Lauwerier E., De Lepeleire J. and Pype P., Resilience in advanced cancer caregiving. A systematic review and meta-synthesis, Palliative Medicine, 2022, pp. 1-15.

Background: Close relatives provide much of the care to people with cancer. As resilience can shield family caregivers from mental health problems, there has been a burgeoning interest in resilience-promoting interventions. However, the evidence necessary for the development of these interventions is scant and unsynthesized.
Aim: To create an overall picture of evidence on resilience in cancer caregiving by a theory-driven meta-synthesis.
Maxime Bellefroid et al.

Bellefroid M, Rodari A, et al. (2022) Role of the cellular factor CTCF in the regulation of bovine leukemia virus latency and three-dimensional chromatin organization. Nucleic Acids Res. Apr 8;50(6):3190-3202. doi: 10.1093/nar/gkac107. PMID: 35234910; PMCID: PMC8989512.

Bovine leukemia virus (BLV)-induced tumoral development is a multifactorial phenomenon that remains incompletely understood. Here, we highlight the critical role of the cellular CCCTC-binding factor (CTCF) both in the regulation of BLV  transcriptional activities and in the deregulation of the three-dimensional (3D) chromatin architecture surrounding the BLV integration site. We demonstrated the in vivo recruitment of CTCF to three conserved CTCF binding motifs along the provirus.

Annaëlle Demaude,* Kitty Baert, David Petitjean, Juliette Zveny, Erik Goormaghtigh, Tom Hauffman, Michael J. Gordon, and François Reniers

Demaude, A., Petitjean,  D.,  Zveny, J., Reniers, F.  et al. (2022) Simple and Scalable Chemical Surface Patterning via Direct Deposition from Immobilized Plasma Filaments in a Dielectric Barrier Discharge. Adv. Sci., 2200237. DOI: 10.1002/advs.202200237

In this work, immobilization of the often unwanted filaments in dielectric barrier discharges (DBD) is achieved and used for one-step deposition of patterned coatings. By texturing one of the dielectric surfaces, a discharge containing stationary plasma filaments is ignited in a mix of argon and propargyl methacrylate (PMA) in a reactor operating at atmospheric pressure. From PMA, hydrophobic and hydrophilic chemical and topographical contrasts at sub-millimeter scale are obtained on silicon and glass substrates.